In this talk I will present a current status of the two-phase (liquid/gas) detector developments at the BINP, Novosibirsk. Motivated by solar neutrino detection, dark matter search and PET for medical application we study the possibility to develop the two-phase detectors with pure noble gases (Ar,Kr,Xe). The primary ionization is amplified by multi-GEM structure in such a detector. The recent results are discussed.